USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: RUVB1_HUMAN USC-OGP 2-DE database:  RUVB1_HUMAN RUVB1_HUMAN General information about the entry View entry in simple text format Entry name RUVB1_HUMAN Primary accession number Q9Y265 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=RuvB-like 1; EC=3.6.4.12; AltName: Full=49 kDa TATA box-binding protein-interacting protein; Short=49 kDa TBP-interacting protein; AltName: Full=54 kDa erythrocyte cytosolic protein; Short=ECP-54; AltName: Full=INO80 complex subunit H; AltName: Full=Nuclear matrix protein 238; Short=NMP 238; AltName: Full=Pontin 52; AltName: Full=TIP49a; AltName: Full=TIP60-associated protein 54-alpha; Short=TAP54-alpha;. Gene name Name=RUVBL1 Synonyms=INO80H, NMP238, TIP49, TIP49A Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0362: pI=6.11; Mw=51463 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1157: pI=6.47; Mw=52149 SPOT OGP-1158: pI=6.01; Mw=51660 Cross-references UniProtKB/Swiss-Prot Q9Y265; RUVB1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name RUVB1_HUMAN Primary accession number Q9Y265 Secondary accession number(s) B2R5S0 P82276 Q1KMR0 Q53HK5 Q53HL7 Q53Y27 Q9BSX9 Sequence was last modified on  November 1, 1999 (version 1) Annotations were last modified on  March 15, 2017 (version 182) Name and origin of the protein Description RecName: Full=RuvB-like 1; EC=3.6.4.12; AltName: Full=49 kDa TATA box-binding protein-interacting protein; Short=49 kDa TBP-interacting protein; AltName: Full=54 kDa erythrocyte cytosolic protein; Short=ECP-54; AltName: Full=INO80 complex subunit H; AltName: Full=Nuclear matrix protein 238; Short=NMP 238; AltName: Full=Pontin 52; AltName: Full=TIP49a; AltName: Full=TIP60-associated protein 54-alpha; Short=TAP54-alpha; Gene name Name=RUVBL1 Synonyms=INO80H, NMP238, TIP49, TIP49A Encoded on Name=RUVBL1; Synonyms=INO80H, NMP238, TIP49, TIP49A Keywords 3D-structure; Acetylation; Activator; Alternative splicing; ATP-binding; Cell cycle; Cell division; Chromatin regulator; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; DNA damage; DNA recombination; DNA repair; Growth regulation; Helicase; Hydrolase; Isopeptide bond; Membrane; Mitosis; Nucleotide-binding; Nucleus; Reference proteome; Transcription; Transcription regulation; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AB012122; BAA28169.1; -; mRNA EMBL AJ010058; CAA08986.1; -; mRNA EMBL AF070735; AAC77819.1; -; mRNA EMBL AF099084; AAD04427.1; -; mRNA EMBL Y18418; CAB46271.1; -; mRNA EMBL AF380344; AAM45570.1; -; Genomic_DNA EMBL AF380343; AAM45570.1; JOINED; Genomic_DNA EMBL DQ469310; ABF13334.1; -; mRNA EMBL BT007057; AAP35706.1; -; mRNA EMBL AK222563; BAD96283.1; -; mRNA EMBL AK222575; BAD96295.1; -; mRNA EMBL AK312290; BAG35217.1; -; mRNA EMBL AB451224; BAG70038.1; -; mRNA EMBL BC002993; AAH02993.1; -; mRNA EMBL BC012886; AAH12886.1; -; mRNA CCDS CCDS3047.1; -. [Q9Y265-1]; . PIR JE0334; JE0334; . RefSeq NP_001306013.1; NM_001319084.1. [Q9Y265-2]; . RefSeq NP_003698.1; NM_003707.2. [Q9Y265-1]; . UniGene Hs.272822; -; . UniGene Hs.710868; -; . PDB 2C9O; X-ray; 2.20 A; A/B/C=1-456 PDB 2XSZ; X-ray; 3.00 A; A/B/C=2-126 A/B/C=234-456 PDBsum; 2C9O; -; . PDBsum 2XSZ; -; . ProteinModelPortal Q9Y265; -; . SMR Q9Y265; -; . BioGrid 114166; 219; . DIP DIP-29937N; -; . IntAct Q9Y265; 93; . MINT MINT-1138777; -; . STRING 9606.ENSP00000318297; -; . BindingDB Q9Y265; -; . ChEMBL CHEMBL3259467; -; . iPTMnet Q9Y265; -; . PhosphoSitePlus Q9Y265; -; . SwissPalm Q9Y265; -; . BioMuta RUVBL1; -; . DMDM 28201891; -; . OGP Q9Y265; -; . REPRODUCTION-2DPAGE Q9Y265; -; . SWISS-2DPAGE Q9Y265; -; . EPD Q9Y265; -; . PaxDb Q9Y265; -; . PeptideAtlas Q9Y265; -; . PRIDE Q9Y265; -; . DNASU 8607; -; . Ensembl ENST00000322623; ENSP00000318297; ENSG00000175792. [Q9Y265-1]; . GeneID 8607; -; . KEGG hsa:8607; -; . UCSC uc003ekh.4; human. [Q9Y265-1]; . CTD 8607; -; . DisGeNET 8607; -; . GeneCards RUVBL1; -; . HGNC HGNC:10474; RUVBL1; . HPA HPA019947; -; . HPA HPA019948; -; . MIM 603449; gene; . neXtProt NX_Q9Y265; -; . OpenTargets ENSG00000175792; -; . PharmGKB PA34887; -; . eggNOG KOG1942; Eukaryota; . eggNOG COG1224; LUCA; . GeneTree ENSGT00550000075043; -; . HOVERGEN HBG054186; -; . InParanoid Q9Y265; -; . KO K04499; -; . OMA YSTSDME; -; . OrthoDB EOG091G07C9; -; . PhylomeDB Q9Y265; -; . TreeFam TF300457; -; . Reactome R-HSA-171319; Telomere Extension By Telomerase; . Reactome R-HSA-201722; Formation of the beta-catenin:TCF transactivating complex; . Reactome R-HSA-3214847; HATs acetylate histones; . Reactome R-HSA-5689603; UCH proteinases; . Reactome R-HSA-5689880; Ub-specific processing proteases; . Reactome R-HSA-5696394; DNA Damage Recognition in GG-NER; . Reactome R-HSA-606279; Deposition of new CENPA-containing nucleosomes at the centromere; . ChiTaRS RUVBL1; human; . EvolutionaryTrace Q9Y265; -; . GeneWiki RuvB-like_1; -; . GenomeRNAi 8607; -; . PRO PR:Q9Y265; -; . Proteomes UP000005640; Chromosome 3; . Bgee ENSG00000175792; -; . CleanEx HS_RUVBL1; -; . ExpressionAtlas Q9Y265; baseline and differential; . Genevisible Q9Y265; HS; . GO GO:0005829; C:cytosol; IDA:HPA; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0031011; C:Ino80 complex; IDA:UniProtKB; . GO GO:0016020; C:membrane; IEA:UniProtKB-SubCell; . GO GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell; . GO GO:0071339; C:MLL1 complex; IDA:UniProtKB; . GO GO:0035267; C:NuA4 histone acetyltransferase complex; IDA:UniProtKB; . GO GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell; . GO GO:0005654; C:nucleoplasm; IDA:HPA; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0097255; C:R2TP complex; IDA:UniProtKB; . GO GO:0000812; C:Swr1 complex; IDA:UniProtKB; . GO GO:0005524; F:ATP binding; IEA:UniProtKB-KW; . GO GO:0043141; F:ATP-dependent 5'-3' DNA helicase activity; IEA:InterPro; . GO GO:0016887; F:ATPase activity; IDA:UniProtKB; . GO GO:0045296; F:cadherin binding; IDA:BHF-UCL; . GO GO:0003678; F:DNA helicase activity; IDA:UniProtKB; . GO GO:1904837; P:beta-catenin-TCF complex assembly; TAS:Reactome; . GO GO:0051301; P:cell division; IEA:UniProtKB-KW; . GO GO:0034080; P:CENP-A containing nucleosome assembly; TAS:Reactome; . GO GO:0006310; P:DNA recombination; IEA:UniProtKB-KW; . GO GO:0006281; P:DNA repair; IEA:UniProtKB-KW; . GO GO:0043968; P:histone H2A acetylation; IDA:UniProtKB; . GO GO:0043967; P:histone H4 acetylation; IDA:UniProtKB; . GO GO:0007067; P:mitotic nuclear division; IEA:UniProtKB-KW; . GO GO:1903955; P:positive regulation of protein targeting to mitochondrion; IMP:ParkinsonsUK-UCL; . GO GO:1904874; P:positive regulation of telomerase RNA localization to Cajal body; IMP:BHF-UCL; . GO GO:0016579; P:protein deubiquitination; TAS:Reactome; . GO GO:0040008; P:regulation of growth; IEA:UniProtKB-KW; . GO GO:1903146; P:regulation of mitophagy; IMP:ParkinsonsUK-UCL; . GO GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc; . GO GO:0007283; P:spermatogenesis; TAS:ProtInc; . GO GO:0006351; P:transcription; DNA-templated; IEA:UniProtKB-KW Gene3D 3.40.50.300; -; 2; . InterPro IPR003593; AAA+_ATPase; . InterPro IPR027417; P-loop_NTPase; . InterPro IPR027238; RuvB-like; . InterPro IPR010339; TIP49_C; . PANTHER PTHR11093; PTHR11093; 1; . Pfam PF06068; TIP49; 1; . SMART SM00382; AAA; 1; . SUPFAM SSF52540; SSF52540; 2; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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